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Signaling by Receptor Tyrosine Kinases (Subject Collection from Cold Spring Harbor Perspectives in Biology)

From Cold Spring Harbor Laboratory Press




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 | #4022919 in Books |  2013-10-31 | Original language:English | PDF # 1 |  7.10 x1.00 x10.30l,2.65 | File type: PDF | 478 pages

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Receptor tyrosine kinases are a large family of cell-surface receptors that respond to a variety of intercellular signals, including insulin, growth factors such as epidermal growth factor (EGF) and fibroblast growth factor (FGF), and molecules involved in neuronal guidance. Ligand binding stimulates the tyrosine kinase activity of the receptors, leading to recruitment of enzymes and adapter proteins that activate intracellular signaling pathways that control cell prolif...

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