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Genetically Engineered Mice for Cancer Research: design, analysis, pathways, validation and pre-clinical testing

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[PDF.od70] Genetically Engineered Mice for Cancer Research: design, analysis, pathways, validation and pre-clinical testing

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 | #5687113 in Books |  2011-12-08 | Original language:English | PDF # 1 |  9.20 x1.50 x6.10l,2.15 | File type: PDF | 632 pages

||From the Back Cover||Technological advances in manipulating the mouse genome has led to the development of sophisticated genetically-engineered models of human cancer that recapitulate many molecular, biologic and histologic features of human tumors.  This

Genetically-engineered mouse models for cancer research have become invaluable tools for studying cancer biology and evaluating novel therapeutic approaches. This volume focuses on state-of-the-art methods for generating, analyzing and validating such models for studying aspects of human cancer biology. Additionally, these models are emerging as important pre-clinical systems in which to test cancer prevention and therapeutic strategies in order to select compounds fo...

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